Kuwait has an ambitious goal to become a financial and trade hub regionally and internationally. The Kuwait Vision of 2035 aims to encourage entrepreneurial activity as a key driver to economic diversification, innovation, and sustainable economic growth. In support of this transformation to the knowledge economy, we are proud to present the first GEM Kuwait National Report 2020/21. This report draws on extensive market research, including collecting high-quality data gathered from 2,092 interviews with residents of Kuwait (between the ages of 18 and 64 years) across all nationalities and genders. The data also gathered 37 carefully chosen Kuwait National Experts across nine framework categories. This study comes at a critical juncture where Kuwait faces unprecedented challenges of global pandemic compounded by an unstable oil price. Therefore, the GEM Kuwait National Report 2020/21 measures the entrepreneurial activity in Kuwait across several dimensions. The study provides insights into the perceptions, attitudes, and activities of Kuwait’s entrepreneurs. The National Report is highly valuable in assessing the entrepreneurship ecosystem in Kuwait, outlines strengths and areas of improvement for entrepreneurial development across the country. The report also examines the level of entrepreneurial activity compared to other economies in the region and internationally. I would like to take this opportunity to congratulate the GEM National Team for this rich report. Also, we would like to thank everyone involved in this collective effort with particular appreciation to our sponsor Kuwait Foundation for the Advancement of Sciences (KFAS). Special thanks go to the GEM Global Team for their continuous support. We hope that this study will serve as a foundation for further discussion and research among scholars and policymakers in Kuwait.